HitPredict

Interactor 1: THOC4 (O08583)
THO complex subunit 4 (Tho4) (Ally of AML-1 and LEF-1) (Aly/REF export factor) (REF1-I) (RNA and export factor-binding protein 1) (Transcriptional coactivator Aly/REF)
Gene: Alyref

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 255 Mm			1 441
+	Hs
		268157 THOC4_HUMAN (1-255): 2.55e-44: 151: 88.72		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		665768 PABP1_MOUSE (96-188): 9.81e-20: 89.8: 27.66		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1257587 RBM39_MOUSE (50-208): 6.99e-16: 78.6: 18.75		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268085 RBM39_HUMAN (50-208): 7.06e-16: 78.6: 18.75		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1208038 MYEF2_MOUSE (22-179): 9.03e-13: 69.5: 22.15		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268312 MYEF2_HUMAN (16-213): 4.74e-10: 61.4: 16.59		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		1201119 THOC4_HUMAN (1-255): 2.55e-44: 151: 88.72		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1201131 THOC4_HUMAN (1-255): 2.55e-44: 151: 88.72		THOC3_HUMAN (148-434): 3.97e-16: 81.3: 19.03
+	Hs
		903346 THOC4_HUMAN (1-255): 2.55e-44: 151: 88.72		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		1281368 PDIP3_HUMAN (52-216): 1.97e-26: 108: 24.56		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		197049 THOC4_HUMAN (1-255): 2.55e-44: 151: 88.72		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51
+	Hs
		1288289 PDIP3_HUMAN (52-216): 1.97e-26: 108: 24.56		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		1054489 RBM39_HUMAN (50-208): 7.06e-16: 78.6: 18.75		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1054500 RBM39_HUMAN (50-208): 7.06e-16: 78.6: 18.75		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		903196 PABP4_HUMAN (96-188): 2.57e-20: 91.7: 27.66		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		516438 PABP1_HUMAN (96-188): 8.84e-20: 90.2: 27.66		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		1031492 PABP4_HUMAN (96-188): 2.57e-20: 91.7: 27.66		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97
+	Hs
		516733 PABP1_HUMAN (96-188): 8.84e-20: 90.2: 27.66		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97
+	Hs
		197019 RBM39_HUMAN (50-208): 7.06e-16: 78.6: 18.75		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51