HitPredict

Interactor 1: PTEN (O08586)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN

Interactor 2: PRDX6 (O08709)
Peroxiredoxin-6 (EC 1.11.1.27) (1-Cys peroxiredoxin) (1-Cys PRX) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Antioxidant protein 2) (Glutathione-dependent peroxiredoxin) (Lysophosphatidylcholine acyltransferase 5) (LPC acyltransferase 5) (LPCAT-5) (Lyso-PC acyltransferase 5) (EC 2.3.1.23) (Non-selenium glutathione peroxidase) (NSGPx)
Gene: PRDX6

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37839992
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 403 Mm			1 224
+	Mm
		139408 PTEN_MOUSE (1-403): 8.54e-168: 477: 100.00		PRDX2_MOUSE (2-204): 2.2e-89: 263: 28.50
+	Hs
		890627 PTEN_HUMAN (1-403): 4.63e-168: 478: 99.75		PRDX1_HUMAN (2-204): 4.46e-86: 255: 28.85
+	Mm
		139330 PTEN_MOUSE (1-403): 8.54e-168: 477: 100.00		PRDX1_MOUSE (2-204): 1.64e-85: 253: 29.33
+	Hs
		670918 PTEN_HUMAN (1-403): 4.63e-168: 478: 99.75		PRDX3_HUMAN (6-204): 6.49e-84: 251: 25.62
+	Mm
		139315 PTEN_MOUSE (1-403): 8.54e-168: 477: 100.00		PRDX3_MOUSE (6-204): 2.35e-83: 250: 25.62
+	Sc
		961483 CDC14_YEAST (17-189): 2.5e-38: 146: 22.70		TSA2_YEAST (5-205): 2.45e-71: 217: 22.44