Interactor 1: PTEN (O08586)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN

Interactor 2: UBP7 (Q6A4J8)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (mHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: Usp7

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 27568561, 37839992, 18716620
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016605 - PML body
GO:0031647 - regulation of protein stability
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 403
Mm

1 1103
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024