HitPredict

Interactor 1: LRIQ1 (Q96JM4)
Leucine-rich repeat- and IQ domain-containing protein 1
Gene: LRRIQ1

Interactor 2: NOTC3 (Q9UM47)
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Gene: NOTCH3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1722 Hs			1 2321
+	Hs
		1047695 LRIQ1_HUMAN (1-1722): 0: 963: 100.00		NOTC2_HUMAN (1047-1646): 7.6e-44: 178: 19.61
+	Dm
		1267158 TOLL7_DROME (1063-1200): 6.19e-10: 66.4: 13.38		Q7YSQ1_DROME (1695-2170): 8.28e-113: 372: 43.75
+	Dm
		451911 Q9VT44_DROME (775-1176): 3.77e-43: 168: 18.68		NOTCH_DROME (989-1644): 4.28e-47: 189: 18.72
+	Hs
		1047620 CEP97_HUMAN (965-1153): 8.78e-15: 82.1: 26.40		NOTC2_HUMAN (1047-1646): 7.6e-44: 178: 19.61
+	Dm
		451780 TOLL7_DROME (1063-1200): 6.19e-10: 66.4: 13.38		NOTCH_DROME (989-1644): 4.28e-47: 189: 18.72
+	Dm
		119678 Q9VT44_DROME (775-1176): 3.77e-43: 168: 18.68		M9PB30_DROME (1026-1494): 3.08e-09: 65.2: 17.20