HitPredict

Interactor 1: SQSTM (O08623)
Sequestosome-1 (Protein kinase C-zeta-interacting protein) (PKC-zeta-interacting protein) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Interactor 2: KPCZ (P09217)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: Prkcz

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.877

The method score is based on:

Property Details
Experiments 26199377, 12431995, 9177193
Identification Methods pull down, two hybrid, enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~PB1, PB1~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0044877 - protein-containing complex binding
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 439
Rn

1 592
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024