Interactor 1: SQSTM (O08623)
Sequestosome-1 (Protein kinase C-zeta-interacting protein) (PKC-zeta-interacting protein) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Interactor 2: IRS1 (P35570)
Insulin receptor substrate 1 (IRS-1) (pp185)
Gene: IRS1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 22761437
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005080 - protein kinase C binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0030674 - protein-macromolecule adaptor activity
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 439
Rn

1 1235
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024