HitPredict

Interactor 1: SQSTM (O08623)
Sequestosome-1 (Protein kinase C-zeta-interacting protein) (PKC-zeta-interacting protein) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Interactor 2: KPCB (P68403)
Protein kinase C beta type (PKC-B) (PKC-beta) (EC 2.7.11.13)
Gene: Prkcb

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	26199377
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PB1~Pkinase
Common GO terms	GO:0005080 - protein kinase C binding GO:0005737 - cytoplasm GO:0006915 - apoptotic process GO:0008270 - zinc ion binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 439 Rn			1 671
+	Rn
		139619 SQSTM_RAT (1-439): 0: 782: 100.00		KPCG_RAT (17-668): 0: 674: 68.11
+	Rn
		139611 SQSTM_RAT (1-439): 0: 782: 100.00		KPCE_RAT (5-668): 0: 612: 44.33
+	Hs
		616709 SQSTM_HUMAN (1-439): 0: 713: 88.46		KS6B1_HUMAN (296-671): 8.8e-159: 469: 37.11
+	Rn
		139610 SQSTM_RAT (1-439): 0: 782: 100.00		KPCD_RAT (2-155): 5e-55: 201: 41.62
+	Mm
		661009 SQSTM_MOUSE (1-439): 0: 772: 96.83		KPCD_MOUSE (2-155): 1.92e-55: 202: 42.24
+	Rn
		139624 SQSTM_RAT (1-439): 0: 782: 100.00		KPCL_RAT (31-206): 2.14e-45: 174: 37.30
+	Hs
		984491 SQSTM_HUMAN (1-439): 0: 713: 88.46		KPCD_HUMAN (6-155): 6.92e-56: 203: 43.95
+	Rn
		94344 SQSTM_RAT (1-439): 0: 782: 100.00		KPCI_RAT (10-86): 5e-13: 74.3: 40.26
+	Rn
		139612 SQSTM_RAT (1-439): 0: 782: 100.00		KPCZ_RAT (10-86): 4.79e-12: 70.9: 36.36
+	Mm
		973811 SQSTM_MOUSE (1-439): 0: 772: 96.83		KPCZ_MOUSE (10-86): 5.31e-12: 70.9: 36.36
+	Hs
		784001 SQSTM_HUMAN (1-439): 0: 713: 88.46		KPCI_HUMAN (10-86): 4.2e-13: 74.3: 40.26
+	Hs
		983828 SQSTM_HUMAN (1-439): 0: 713: 88.46		KPCZ_HUMAN (10-86): 4.35e-12: 71.2: 36.36
+	Dm
		54642 REF2P_DROME (110-167): 1.12e-17: 87.5: 41.67		APKC_DROME (4-86): 7.39e-14: 77: 39.76