HitPredict

Interactor 1: MARK2 (O08679)
Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2)
Gene: MARK2

Interactor 2: MARK2 (O08679)
Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2)
Gene: MARK2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 16472737
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains KA1~Pkinase, KA1~UBA, Pkinase~Pkinase, Pkinase~UBA, UBA~UBA
Common GO terms GO:0000226 - microtubule cytoskeleton organization
GO:0000287 - magnesium ion binding
GO:0001764 - neuron migration
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
and 31 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 722
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Last updated: 15 Jul 2024