Interactor 1: UNC5B (O08722)
Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B)
Gene: UNC5B

Interactor 2: AGAP2 (Q8CGU4)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 18469807
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~I-set
Common GO terms GO:0006915 - apoptotic process
GO:0043524 - negative regulation of neuron apoptotic process
GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO:2001240 - negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 945
Rn

1 1186
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024