HitPredict

Interactor 1: RGS12 (O08774)
Regulator of G-protein signaling 12 (RGS12)
Gene: RGS12

Interactor 2: RASN (Q04970)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: Nras

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	17380122
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, RBD~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1387 Rn			1 189
+	Rn
		139845 RGS12_RAT (1-1387): 0: 1951: 100.00		RASH_RAT (1-188): 5.36e-78: 232: 85.11
+	Hs
		158596 RGS12_HUMAN (1-1384): 0: 1831: 83.69		RASH_HUMAN (1-188): 5.36e-78: 232: 85.11
+	Hs
		207504 RGS14_HUMAN (673-1242): 2.34e-177: 540: 38.62		RASH_HUMAN (1-188): 5.36e-78: 232: 85.11
+	Mm
		956619 RGS14_MOUSE (673-1235): 3.68e-171: 523: 39.52		RAB35_MOUSE (4-171): 6.03e-84: 247: 34.71
+	Dm
		443011 Q9VCX2_DROME (573-1203): 6.16e-155: 501: 25.15		RAS1_DROME (1-170): 2.97e-90: 263: 83.53
+	Mm
		867148 RGS14_MOUSE (673-1235): 3.68e-171: 523: 39.52		RAB2A_MOUSE (4-185): 1.11e-74: 224: 31.52
+	Mm
		918978 RGS14_MOUSE (673-1235): 3.68e-171: 523: 39.52		RAB1A_MOUSE (4-185): 8.56e-75: 224: 33.70
+	Hs
		207516 RGS14_HUMAN (673-1242): 2.34e-177: 540: 38.62		RAP1A_HUMAN (1-165): 1.31e-60: 188: 56.29
+	Dm
		442973 Q9VCX2_DROME (573-1203): 6.16e-155: 501: 25.15		RAP1_DROME (1-163): 7.34e-63: 194: 59.15
+	Dm
		443010 RGS_DROME (9-442): 6.74e-114: 394: 30.53		RAS1_DROME (1-170): 2.97e-90: 263: 83.53
+	Dm
		442972 RGS_DROME (9-442): 6.74e-114: 394: 30.53		RAP1_DROME (1-163): 7.34e-63: 194: 59.15
+	Hs
		782022 RGS2_HUMAN (639-840): 9.39e-59: 203: 25.12		RAB2A_HUMAN (4-185): 1.76e-74: 224: 31.52
+	Hs
		782023 RGS2_HUMAN (639-840): 9.39e-59: 203: 25.12		RAP1B_HUMAN (1-165): 1.02e-61: 191: 56.89