HitPredict

Interactor 1: DIAP1 (O08808)
Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (p140mDIA) (mDIA1)
Gene: Diaph1

Interactor 2: YES (Q04736)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: Yes1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18194650
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005884 - actin filament GO:0044325 - transmembrane transporter binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1255 Mm			1 541
+	Hs
		237552 DIAP1_HUMAN (1-1255): 0: 930: 89.54		HCK_HUMAN (1-539): 0: 551: 57.89
+	Mm
		139938 DIAP1_MOUSE (744-1255): 1.62e-150: 488: 100.00		SRC_MOUSE (1-541): 0: 607: 73.01
+	Mm
		139941 DIAP1_MOUSE (744-1255): 1.62e-150: 488: 100.00		FYN_MOUSE (1-541): 0: 603: 72.61
+	Hs
		433952 FMNL2_HUMAN (58-1206): 6.06e-169: 532: 17.00		LYN_HUMAN (1-539): 0: 537: 53.33
+	Ce
		109512 H2KYI3_CAEEL (13-569): 1.44e-58: 224: 18.52		SRC2_CAEEL (34-539): 1.11e-177: 512: 51.37
+	Ce
		106635 H2KYI3_CAEEL (13-569): 1.44e-58: 224: 18.52		SRC1_CAEEL (1-539): 7.44e-176: 508: 47.37
+	Hs
		411876 FMN2_HUMAN (730-1149): 8.17e-21: 101: 25.93		LCK_HUMAN (31-539): 0: 547: 55.38
+	Hs
		434041 FMN2_HUMAN (730-1149): 8.17e-21: 101: 25.93		LYN_HUMAN (1-539): 0: 537: 53.33
+	Ce
		220203 O61701_CAEEL (262-569): 3.73e-22: 105: 19.27		SRC2_CAEEL (34-539): 1.11e-177: 512: 51.37
+	Ce
		106647 O61701_CAEEL (262-569): 3.73e-22: 105: 19.27		SRC1_CAEEL (1-539): 7.44e-176: 508: 47.37
+	Ce
		106691 Q9BL72_CAEEL (71-231): 1.99e-12: 74.3: 17.39		SRC1_CAEEL (1-539): 7.44e-176: 508: 47.37