HitPredict

Interactor 1: BIRC3 (O08863)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 2) (C-IAP2) (Inhibitor of apoptosis protein 1) (mIAP1) (RING-type E3 ubiquitin transferase BIRC3)
Gene: BIRC3

Interactor 2: TRAF2 (P39429)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2)
Gene: TRAF2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 21765415, 11181075, 15102471
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BIR~TRAF_BIRC3_bd
Common GO terms GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0032991 - protein-containing complex
GO:0043066 - negative regulation of apoptotic process
GO:0044877 - protein-containing complex binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024