Interactor 1: BIRC3 (O08863)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 2) (C-IAP2) (Inhibitor of apoptosis protein 1) (mIAP1) (RING-type E3 ubiquitin transferase BIRC3)
Gene: BIRC3

Interactor 2: FADD (Q61160)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity)
Gene: FADD

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 18708583
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~Death
Common GO terms GO:0006915 - apoptotic process
GO:0032991 - protein-containing complex
GO:0044877 - protein-containing complex binding
GO:0060546 - negative regulation of necroptotic process
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 600
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1 205
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Last updated: 15 Jul 2024