HitPredict

Interactor 1: MK12 (O08911)
Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)
Gene: Mapk12

Interactor 2: MK14 (P47811)
Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (CRK1) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha)
Gene: Mapk14

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 15102471
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 4 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 367
Mm

1 360
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Sc
+ Sp
+ Hs
+ At
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024