HitPredict

Interactor 1: HDAC1 (O09106)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: TAL1 (P22091)
T-cell acute lymphocytic leukemia protein 1 homolog (TAL-1) (Stem cell protein)
Gene: TAL1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

The method score is based on:

Property	Details
Experiments	10688671, 19497860, 16407974
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000976 - transcription cis-regulatory region binding GO:0003677 - DNA binding GO:0003682 - chromatin binding and 9 others more... GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex GO:0032991 - protein-containing complex GO:0042826 - histone deacetylase binding GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0070888 - E-box binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	482
Mm

1	329

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024