HitPredict

Interactor 1: HDAC1 (O09106)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: BACH1 (P97302)
Transcription regulator protein BACH1 (BTB and CNC homolog 1)
Gene: BACH1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	19011633
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Mm			1 739
+	Hs
		157201 HDAC1_HUMAN (1-482): 0: 666: 99.38		BACH1_HUMAN (1-739): 0: 552: 79.73
+	Hs
		177376 HDAC3_HUMAN (9-434): 0: 572: 58.18		BACH2_HUMAN (1-739): 4.17e-124: 392: 30.00
+	Hs
		1038367 HDAC1_HUMAN (1-482): 0: 666: 99.38		KEAP1_HUMAN (2-427): 3.15e-66: 232: 16.52
+	Hs
		1038415 HDAC1_HUMAN (1-482): 0: 666: 99.38		NF2L2_HUMAN (406-660): 4.08e-66: 231: 26.20
+	Dm
		996071 HDAC1_DROME (6-477): 0: 656: 77.33		GAGA_DROME (1-363): 9.06e-70: 241: 17.74
+	Hs
		1081235 HDAC2_HUMAN (1-478): 0: 664: 86.13		NF2L2_HUMAN (406-660): 4.08e-66: 231: 26.20
+	Hs
		1038838 HDAC1_HUMAN (1-482): 0: 666: 99.38		ZBTB1_HUMAN (14-628): 2.26e-60: 218: 15.18
+	Mm
		140211 HDAC1_MOUSE (1-482): 0: 670: 100.00		ZBT7A_MOUSE (13-191): 1.1e-42: 165: 27.78
+	Hs
		312063 HDAC1_HUMAN (1-482): 0: 666: 99.38		ZBT7A_HUMAN (13-181): 4.75e-42: 163: 28.82
+	Hs
		312081 HDAC2_HUMAN (1-478): 0: 664: 86.13		ZBT7A_HUMAN (13-181): 4.75e-42: 163: 28.82
+	Hs
		200286 HDAC1_HUMAN (1-482): 0: 666: 99.38		ZBT43_HUMAN (4-213): 5.1e-40: 155: 22.62
+	Hs
		177307 HDAC3_HUMAN (9-434): 0: 572: 58.18		NF2L2_HUMAN (406-660): 4.08e-66: 231: 26.20
+	Hs
		1038527 HDAC1_HUMAN (1-482): 0: 666: 99.38		BCL6B_HUMAN (9-130): 8.37e-14: 76.6: 35.77
+	Hs
		781362 HDAC1_HUMAN (1-482): 0: 666: 99.38		BCL6_HUMAN (16-127): 2.49e-13: 75.5: 37.17
+	Hs
		781407 HDAC2_HUMAN (1-478): 0: 664: 86.13		BCL6_HUMAN (16-127): 2.49e-13: 75.5: 37.17
+	Hs
		177160 HDAC3_HUMAN (9-434): 0: 572: 58.18		ZBT7A_HUMAN (13-181): 4.75e-42: 163: 28.82
+	Hs
		1038614 HDAC1_HUMAN (1-482): 0: 666: 99.38		ZBTB9_HUMAN (16-127): 3.11e-11: 68.2: 34.82
+	Hs
		177221 HDAC3_HUMAN (9-434): 0: 572: 58.18		BCL6_HUMAN (16-127): 2.49e-13: 75.5: 37.17
+	Mm
		1257439 Q9JM08_MOUSE (9-434): 0: 566: 57.94		ZBT7C_MOUSE (16-127): 4.07e-13: 74.7: 35.40
+	Hs
		781402 HDAC7_HUMAN (11-410): 2.87e-136: 417: 21.38		BCL6_HUMAN (16-127): 2.49e-13: 75.5: 37.17