HitPredict

Interactor 1: HDAC1 (O09106)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: FOXP3 (Q99JB6)
Forkhead box protein P3 (Scurfin) [Cleaved into: Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form]
Gene: FOXP3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 22922362, 26365427
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 6 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 482
Mm

1 429
+ Mm
+ Hs
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+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs
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+ Sp
+ Hs

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Last updated: 15 Jul 2024