HitPredict

Interactor 1: NET1 (O09118)
Netrin-1
Gene: Ntn1

Interactor 2: DSCAM (Q9ERC8)
Cell adhesion molecule DSCAM (Down syndrome cell adhesion molecule homolog)
Gene: DSCAM

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	26633812, 18585357
Identification Methods	pull down, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Laminin_EGF~fn3, Laminin_N~fn3
Common GO terms	GO:0007411 - axon guidance
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 604 Mm			1 2013
+	Mm
		1113178 NET5_MOUSE (341-602): 7.3e-53: 189: 38.27		DSCAM_MOUSE (1-2013): 0: 1288: 100.00
+	Mm
		140333 NET1_MOUSE (1-604): 1.19e-175: 512: 100.00		DCC_MOUSE (5-988): 1.05e-91: 331: 15.76
+	Hs
		317787 NET1_HUMAN (1-604): 8.42e-176: 513: 99.17		DCC_HUMAN (1-988): 1.32e-89: 325: 15.08
+	Dr
		3056 O42140_DANRE (2-604): 4.08e-178: 519: 85.90		A0A0R4IP15_DANRE (885-1998): 1.19e-62: 239: 14.80
+	Dr
		3055 F1QUK5_DANRE (2-601): 7.72e-171: 500: 80.40		A0A0R4IP15_DANRE (885-1998): 1.19e-62: 239: 14.80
+	Dr
		193793 O42140_DANRE (2-604): 4.08e-178: 519: 85.90		Q49BB0_DANRE (13-415): 6.22e-47: 188: 19.58
+	Mm
		936323 NET4_MOUSE (9-597): 1.06e-101: 323: 28.59		DCC_MOUSE (5-988): 1.05e-91: 331: 15.76
+	Hs
		793659 NET4_HUMAN (9-598): 9.29e-104: 328: 28.55		DCC_HUMAN (1-988): 1.32e-89: 325: 15.08
+	Hs
		317794 NET1_HUMAN (1-604): 8.42e-176: 513: 99.17		NEO1_HUMAN (8-305): 2.4e-12: 74.7: 11.22
+	Hs
		1271866 NET4_HUMAN (9-598): 9.29e-104: 328: 28.55		NEO1_HUMAN (8-305): 2.4e-12: 74.7: 11.22
+	Dm
		1099064 NETB_DROME (32-253): 1.38e-49: 186: 53.88		Q9W213_DROME (100-506): 9.92e-26: 118: 27.57
+	Hs
		631060 LAMA1_HUMAN (423-575): 2.21e-09: 62.9: 14.75		PGBM_HUMAN (24-145): 2.22e-09: 65.2: 13.01