Interactor 1: GSH0 (O09172)
Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit)
Gene: Gclm

Interactor 2: GSH1 (P97494)
Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase)
Gene: Gclc

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 16081425
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004357 - glutamate-cysteine ligase activity
GO:0006534 - cysteine metabolic process
GO:0006536 - glutamate metabolic process
GO:0006749 - glutathione metabolic process
GO:0006750 - glutathione biosynthetic process
and 17 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 274
Mm

1 637
+ Rn
+ Hs
+ Ce
+ Ce
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024