HitPredict

Interactor 1: INCEA (O13024)
Inner centromere protein A (XL-INCENP) (xINC) (xIncenp) (Mitotic phosphoprotein 130)
Gene: incenp-a

Interactor 2: AUKBA (Q6DE08)
Aurora kinase B-A (EC 2.7.11.1) (Aurora/IPL1-related kinase 2-A) (AIRK2-A) (XAIRK2-A) (Serine/threonine-protein kinase 12-A) (Serine/threonine-protein kinase aurora-B-A) (xAurora-B)
Gene: aurkb-a

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.812

The method score is based on:

Property Details
Experiments 10996078, 15866179
Identification Methods affinity chromatography technology, pull down, x-ray crystallography
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains INCENP_ARK-bind~Pkinase
Common GO terms GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005694 - chromosome
GO:0030496 - midbody
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 873
Xl

1 361
+ Xl
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024