HitPredict

Interactor 1: EFNB1 (O13097)
Ephrin-B1 (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (XlERK)
Gene: EFNB1

Interactor 2: Q6V1R3 (Q6V1R3)
Cytoplasmic protein
Gene: nck2.L

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	14535844
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 329 Xl			1 381
+	Hs
		209030 EFNB1_HUMAN (5-329): 5.63e-164: 462: 72.43		NCK2_HUMAN (1-381): 6.92e-90: 277: 82.68
+	Mm
		223007 EFNB1_MOUSE (10-329): 5.51e-160: 452: 73.25		NCK2_MOUSE (1-381): 1.02e-89: 277: 80.58
+	Hs
		209015 EFNB2_HUMAN (5-329): 4.7e-156: 441: 57.27		NCK2_HUMAN (1-381): 6.92e-90: 277: 82.68
+	Mm
		223008 EFNB2_MOUSE (5-329): 5.26e-155: 439: 57.58		NCK2_MOUSE (1-381): 1.02e-89: 277: 80.58
+	Hs
		129276 EFNB1_HUMAN (5-329): 5.63e-164: 462: 72.43		P85B_HUMAN (16-381): 3.05e-23: 103: 14.36
+	Hs
		655281 EFNB2_HUMAN (5-329): 4.7e-156: 441: 57.27		P85A_HUMAN (12-380): 2.47e-25: 109: 12.07
+	Hs
		129251 EFNB2_HUMAN (5-329): 4.7e-156: 441: 57.27		P85B_HUMAN (16-381): 3.05e-23: 103: 14.36
+	Hs
		522911 EFNB1_HUMAN (5-329): 5.63e-164: 462: 72.43		SRC_HUMAN (5-149): 1.49e-15: 80.2: 14.29
+	Hs
		522869 EFNA5_HUMAN (7-189): 2.38e-69: 217: 26.56		SRC_HUMAN (5-149): 1.49e-15: 80.2: 14.29