HitPredict

Interactor 1: RS9A (O13516)
Small ribosomal subunit protein uS4A (40S ribosomal protein S9-A) (RP21) (S13) (YP28) (YS11)
Gene: RPS9A

Interactor 2: PWP2 (P25635)
Periodic tryptophan protein 2 (U three protein 1) (U3 small nucleolar RNA-associated protein 1) (U3 snoRNA-associated protein 1)
Gene: PWP2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	12150911, 16429126, 35650250
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0030686 - 90S preribosome and 1 others more... GO:0032040 - small-subunit processome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 197 Sc			1 923
+	Sc
		407478 RS9B_YEAST (1-180): 4.47e-79: 236: 99.44		PWP2_YEAST (1-923): 0: 650: 100.00
+	Sc
		635560 IMP3_YEAST (19-162): 7.66e-60: 186: 22.92		PWP2_YEAST (1-923): 0: 650: 100.00
+	Hs
		1070048 IMP3_HUMAN (19-162): 1.81e-53: 170: 24.83		PWP2_HUMAN (1-897): 1.24e-171: 524: 40.41
+	Sc
		141450 RS9A_YEAST (1-185): 3.05e-81: 241: 100.00		COPA_YEAST (1-447): 1.7e-49: 192: 12.05
+	Hs
		792939 RS9_HUMAN (9-193): 1.61e-78: 234: 69.73		LIS1_HUMAN (564-720): 5.47e-17: 86.5: 10.06
+	Hs
		807027 RS9_HUMAN (9-193): 1.61e-78: 234: 69.73		NLE1_HUMAN (669-882): 5.38e-12: 71: 11.66
+	Hs
		806797 RS9_HUMAN (9-193): 1.61e-78: 234: 69.73		GBB2_HUMAN (342-550): 1.77e-09: 62.4: 21.46
+	Sc
		700114 IMP3_YEAST (19-162): 7.66e-60: 186: 22.92		UTP12_YEAST (1-122): 1.57e-21: 103: 15.20
+	Hs
		1288333 IMP3_HUMAN (19-162): 1.81e-53: 170: 24.83		SNR40_HUMAN (143-502): 1.03e-16: 84.7: 22.28