HitPredict

Interactor 1: YTHD1 (Q9BYJ9)
YTH domain-containing family protein 1 (DF1) (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1)
Gene: YTHDF1

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29395067, 39501047
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005737 - cytoplasm GO:0010494 - cytoplasmic stress granule GO:0034063 - stress granule assembly
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 559 Hs			1 482
+	Hs
		1462243 YTHD2_HUMAN (1-558): 9.3e-138: 413: 62.72		G3BP2_HUMAN (1-482): 6.03e-108: 330: 100.00
+	Hs
		1280772 YTHD3_HUMAN (1-541): 2.09e-130: 394: 65.91		G3BP2_HUMAN (1-482): 6.03e-108: 330: 100.00
+	Hs
		1101011 YTHD1_HUMAN (1-559): 1.17e-140: 420: 100.00		G3BP1_HUMAN (1-460): 6.21e-83: 265: 56.81
+	Hs
		1101121 YTHD2_HUMAN (1-558): 9.3e-138: 413: 62.72		G3BP1_HUMAN (1-460): 6.21e-83: 265: 56.81
+	Hs
		1100864 YTHD3_HUMAN (1-541): 2.09e-130: 394: 65.91		G3BP1_HUMAN (1-460): 6.21e-83: 265: 56.81
+	Hs
		1369832 YTHD1_HUMAN (1-559): 1.17e-140: 420: 100.00		CELF1_HUMAN (323-419): 5.01e-15: 79.2: 18.63
+	Hs
		1369888 YTHD2_HUMAN (1-558): 9.3e-138: 413: 62.72		CELF1_HUMAN (323-419): 5.01e-15: 79.2: 18.63
+	Hs
		1280712 YTHD3_HUMAN (1-541): 2.09e-130: 394: 65.91		CELF1_HUMAN (323-419): 5.01e-15: 79.2: 18.63
+	Hs
		925713 SC24C_HUMAN (10-290): 5.09e-10: 64.6: 12.37		G3BP1_HUMAN (1-460): 6.21e-83: 265: 56.81