Interactor 1: NEMO (Q9GYV5)
NF-kappa-B essential modulator (Inhibitor of nuclear factor kappa B kinase subunit gamma) (DmIKKgamma) (NEMO homolog)
Gene: key

Interactor 2: IKKB (Q9VEZ5)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappaB kinase subunit beta) (EC 2.7.11.10) (Cactus kinase IKK) (IKK-like protein) (Immune response deficient protein 5) (Lipopolysaccharide-activated kinase) (DLAK)
Gene: IKKbeta

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.55 0.683

The method score is based on:

Property Details
Experiments 11018014, 29097655, 23749869, 22036573, 38944040
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002230 - positive regulation of defense response to virus by host
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006963 - positive regulation of antibacterial peptide biosynthetic process
GO:0030163 - protein catabolic process
and 4 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025