HitPredict

Interactor 1: CUL1 (O13790)
Cullin-1 (Cul-1) (Cell division control 53 homolog)
Gene: CUL1

Interactor 2: UBL1 (O14399)
Ubiquitin-like protein 1
Gene: UBL1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	11854407, 10880460
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cullin~ubiquitin, Cullin_Nedd8~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0019005 - SCF ubiquitin ligase complex GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 767 Sp			1 78
+	Hs
		1041004 CUL1_HUMAN (4-767): 0: 800: 40.66		NEDD8_HUMAN (1-76): 5.41e-34: 112: 81.58
+	Hs
		923983 CUL3_HUMAN (9-767): 0: 773: 28.55		RS27A_HUMAN (1-77): 9.47e-37: 122: 53.25
+	Hs
		923984 CUL4A_HUMAN (7-767): 0: 770: 28.79		RS27A_HUMAN (1-77): 9.47e-37: 122: 53.25
+	Hs
		1041658 CUL3_HUMAN (9-767): 0: 773: 28.55		NEDD8_HUMAN (1-76): 5.41e-34: 112: 81.58
+	Hs
		924296 CUL4A_HUMAN (7-767): 0: 770: 28.79		RL40_HUMAN (1-76): 5.25e-34: 114: 53.95
+	Hs
		1043010 CUL4A_HUMAN (7-767): 0: 770: 28.79		NEDD8_HUMAN (1-76): 5.41e-34: 112: 81.58
+	Dm
		1097203 CUL1_DROME (13-767): 0: 763: 39.43		NEDD8_DROME (1-77): 1.01e-34: 114: 80.52
+	At
		1352191 CUL3A_ARATH (7-767): 0: 779: 29.34		RUB1_ARATH (3-76): 2.92e-27: 97.9: 82.43
+	Hs
		923985 CUL4B_HUMAN (7-767): 0: 753: 28.79		RS27A_HUMAN (1-77): 9.47e-37: 122: 53.25
+	Hs
		1043371 CUL4B_HUMAN (7-767): 0: 753: 28.79		NEDD8_HUMAN (1-76): 5.41e-34: 112: 81.58
+	Hs
		475024 CUL4B_HUMAN (7-767): 0: 753: 28.79		UBB_HUMAN (1-76): 1.13e-31: 111: 53.95
+	At
		1321116 CUL3B_ARATH (7-767): 0: 766: 29.60		RUB1_ARATH (3-76): 2.92e-27: 97.9: 82.43
+	Dm
		1213846 Q8IP45_DROME (8-767): 0: 745: 27.18		NEDD8_DROME (1-77): 1.01e-34: 114: 80.52
+	Hs
		1041337 CUL2_HUMAN (14-767): 0: 732: 30.40		NEDD8_HUMAN (1-76): 5.41e-34: 112: 81.58
+	At
		1091919 CUL1_ARATH (13-767): 0: 730: 27.74		UBQ3_ARATH (1-76): 4.9e-30: 109: 52.63
+	At
		1277343 CUL1_ARATH (13-767): 0: 730: 27.74		RUB1_ARATH (3-76): 2.92e-27: 97.9: 82.43
+	At
		1247030 CUL1_ARATH (13-767): 0: 730: 27.74		RUB2_ARATH (3-76): 3.77e-26: 95.2: 82.43
+	Ce
		1088883 CUL3_CAEEL (16-767): 0: 676: 27.25		NEDD8_CAEEL (1-76): 4.65e-35: 115: 82.90
+	Sc
		977843 CDC53_YEAST (13-767): 0: 668: 31.75		RUB1_YEAST (1-77): 3.74e-22: 82.8: 59.74
+	Sp
		145590 CUL3_SCHPO (16-767): 0: 617: 25.25		UBL1_SCHPO (1-78): 1.56e-33: 111: 100.00