HitPredict

Interactor 1: CUL1 (O13790)
Cullin-1 (Cul-1) (Cell division control 53 homolog)
Gene: CUL1

Interactor 2: CSN2 (Q9HFR0)
COP9 signalosome complex subunit 2 (CSN complex subunit 2) (SGN2)
Gene: CSN2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	11337588, 32047038, 23535663
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000822 - inositol hexakisphosphate binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 767 Sp			1 437
+	Mm
		897343 CUL1_MOUSE (4-767): 0: 803: 40.79		CSN2_MOUSE (1-435): 5.12e-140: 409: 46.10
+	Hs
		897242 CUL1_HUMAN (4-767): 0: 800: 40.66		CSN2_HUMAN (1-435): 5.12e-140: 409: 46.10
+	Hs
		897244 CUL3_HUMAN (9-767): 0: 773: 28.55		CSN2_HUMAN (1-435): 5.12e-140: 409: 46.10
+	Hs
		897245 CUL4A_HUMAN (7-767): 0: 770: 28.79		CSN2_HUMAN (1-435): 5.12e-140: 409: 46.10
+	At
		1258869 CUL3A_ARATH (7-767): 0: 779: 29.34		CSN2_ARATH (9-437): 3.41e-130: 384: 45.48
+	Hs
		897246 CUL4B_HUMAN (7-767): 0: 753: 28.79		CSN2_HUMAN (1-435): 5.12e-140: 409: 46.10
+	Hs
		897243 CUL2_HUMAN (14-767): 0: 732: 30.40		CSN2_HUMAN (1-435): 5.12e-140: 409: 46.10
+	Hs
		1041600 CUL3_HUMAN (9-767): 0: 773: 28.55		PSMD6_HUMAN (102-436): 5.27e-104: 315: 12.43
+	Hs
		1024157 CUL1_HUMAN (4-767): 0: 800: 40.66		CSN1_HUMAN (117-425): 8.13e-73: 238: 10.17
+	Sp
		142912 CUL1_SCHPO (1-767): 0: 829: 100.00		CSN1_SCHPO (114-436): 2.03e-62: 209: 14.12
+	Hs
		1041179 CUL1_HUMAN (4-767): 0: 800: 40.66		CSN4_HUMAN (73-411): 2.86e-69: 226: 13.52
+	Hs
		1024159 CUL3_HUMAN (9-767): 0: 773: 28.55		CSN1_HUMAN (117-425): 8.13e-73: 238: 10.17
+	Hs
		1024160 CUL4A_HUMAN (7-767): 0: 770: 28.79		CSN1_HUMAN (117-425): 8.13e-73: 238: 10.17
+	Hs
		1042418 CUL3_HUMAN (9-767): 0: 773: 28.55		CSN4_HUMAN (73-411): 2.86e-69: 226: 13.52
+	Hs
		1043195 CUL4A_HUMAN (7-767): 0: 770: 28.79		CSN4_HUMAN (73-411): 2.86e-69: 226: 13.52
+	Hs
		1024161 CUL4B_HUMAN (7-767): 0: 753: 28.79		CSN1_HUMAN (117-425): 8.13e-73: 238: 10.17
+	Hs
		1043547 CUL4B_HUMAN (7-767): 0: 753: 28.79		CSN4_HUMAN (73-411): 2.86e-69: 226: 13.52
+	Hs
		87385 CUL4B_HUMAN (7-767): 0: 753: 28.79		C9JFE4_HUMAN (112-425): 3.72e-66: 220: 10.14
+	Hs
		1024158 CUL2_HUMAN (14-767): 0: 732: 30.40		CSN1_HUMAN (117-425): 8.13e-73: 238: 10.17
+	Hs
		1041454 CUL2_HUMAN (14-767): 0: 732: 30.40		CSN4_HUMAN (73-411): 2.86e-69: 226: 13.52