HitPredict

Interactor 1: YE02 (O13799)
Uncharacterized helicase C17H9.02 (EC 3.6.4.-)
Gene: SPAC17H9.02

Interactor 2: PAB2 (O14327)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Poly(A)-binding protein II) (PABII)
Gene: PAB2

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	24210919, 24713849, 25989903
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0016604 - nuclear body GO:0033621 - nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1030 Sp			1 166
+	Hs
		786913 MTREX_HUMAN (28-1030): 0: 846: 46.72		NCBP2_HUMAN (18-163): 7.02e-33: 116: 20.41
+	Sp
		145110 MTR4_SCHPO (1-1030): 0: 801: 48.66		PAB2_SCHPO (1-166): 2.28e-39: 132: 100.00
+	Sp
		143177 YE02_SCHPO (1-1030): 0: 808: 100.00		NCBP2_SCHPO (54-164): 2.97e-31: 112: 28.57
+	Sc
		810941 MTR4_YEAST (45-1030): 0: 766: 46.52		NCBP2_YEAST (32-166): 2.48e-32: 116: 26.95
+	Hs
		571369 DDX5_HUMAN (38-595): 2.41e-111: 359: 11.30		NCBP2_HUMAN (18-163): 7.02e-33: 116: 20.41
+	Hs
		516589 ASCC3_HUMAN (104-654): 1.95e-106: 368: 18.14		PABP1_HUMAN (3-144): 5.34e-24: 99.2: 16.78
+	Sc
		624191 DBP2_YEAST (2-549): 6.35e-107: 346: 11.75		NCBP2_YEAST (32-166): 2.48e-32: 116: 26.95
+	Hs
		134106 DDX3X_HUMAN (2-554): 4.17e-102: 336: 12.46		PABP2_HUMAN (2-166): 4.13e-33: 120: 44.94
+	Mm
		857351 Q8BTS0_MOUSE (38-595): 2.43e-111: 359: 11.30		TIA1_MOUSE (50-143): 3.76e-20: 87.3: 18.95
+	Sc
		416100 DED1_YEAST (39-548): 8.66e-100: 328: 12.52		NCBP2_YEAST (32-166): 2.48e-32: 116: 26.95
+	Mm
		936480 DDX5_MOUSE (38-595): 2.44e-111: 359: 11.30		TIAR_MOUSE (49-143): 5.53e-17: 78.4: 14.41
+	Mm
		857323 DDX17_MOUSE (39-554): 2.15e-106: 348: 11.55		TIA1_MOUSE (50-143): 3.76e-20: 87.3: 18.95
+	Hs
		133858 DDX3X_HUMAN (2-554): 4.17e-102: 336: 12.46		PABP1_HUMAN (3-144): 5.34e-24: 99.2: 16.78
+	Hs
		134018 DDX3X_HUMAN (2-554): 4.17e-102: 336: 12.46		PABP4_HUMAN (3-139): 5.85e-24: 98.8: 18.12
+	Hs
		272072 U520_HUMAN (40-567): 3.28e-81: 292: 19.76		NCBP2_HUMAN (18-163): 7.02e-33: 116: 20.41
+	Sc
		697273 BRR2_YEAST (51-621): 1.12e-34: 146: 15.05		NCBP2_YEAST (32-166): 2.48e-32: 116: 26.95