Interactor 1: GHC2 (Q9H1K4)
Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+) symporter 2) (Solute carrier family 25 member 18)
Gene: SLC25A18

Interactor 2: GHC1 (Q9H936)
Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22)
Gene: SLC25A22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 34349018, 35575683, unassigned3795
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Mito_carr~Mito_carr
Common GO terms GO:0005280 - amino acid:proton symporter activity
GO:0005313 - L-glutamate transmembrane transporter activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006811 - monoatomic ion transport
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 315
Hs

1 323
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Last updated: 11Aug2025