HitPredict

Interactor 1: RPF2 (Q9H7B2)
Ribosome production factor 2 homolog (Brix domain-containing protein 1) (Ribosome biogenesis protein RPF2 homolog)
Gene: RPF2

Interactor 2: NOP53 (Q9NZM5)
Ribosome biogenesis protein NOP53 (Glioma tumor suppressor candidate region gene 2 protein) (Protein interacting with carboxyl terminus 1) (PICT-1) (p60)
Gene: NOP53

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

The method score is based on:

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000027 - ribosomal large subunit assembly GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0008097 - 5S rRNA binding and 2 others more... GO:1901796 - regulation of signal transduction by p53 class mediator GO:1902570 - protein localization to nucleolus
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	306
Hs

1	478

Service provided by Combinatics, Japan

Last updated: 11Aug2025