HitPredict

Interactor 1: PPK9 (O13945)
Protein kinase domain-containing protein ppk9
Gene: PPK9

Interactor 2: AAKG (Q10343)
5'-AMP-activated protein kinase subunit gamma (AMPK gamma) (AMPK subunit gamma)
Gene: cbs2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19371376
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AdenylateSensor~CBS
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 532 Sp			1 334
+	Hs
		1025235 AAPK1_HUMAN (7-519): 2.45e-155: 456: 29.96		AAKG2_HUMAN (3-328): 8.47e-107: 325: 32.52
+	Hs
		871497 AAPK2_HUMAN (9-528): 2.35e-154: 454: 28.93		AAKG2_HUMAN (3-328): 8.47e-107: 325: 32.52
+	Hs
		1025234 AAPK1_HUMAN (7-519): 2.45e-155: 456: 29.96		AAKG3_HUMAN (5-321): 3.42e-106: 320: 31.25
+	Rn
		871248 AAPK1_RAT (7-519): 1.05e-154: 455: 29.96		AAKG1_RAT (4-322): 4.64e-108: 320: 32.92
+	Hs
		871496 AAPK2_HUMAN (9-528): 2.35e-154: 454: 28.93		AAKG3_HUMAN (5-321): 3.42e-106: 320: 31.25
+	Mm
		222739 AAPK1_MOUSE (7-519): 1.82e-153: 451: 29.96		AAKG1_MOUSE (4-322): 7.6e-109: 322: 32.92
+	Hs
		871006 AAPK1_HUMAN (7-519): 2.45e-155: 456: 29.96		AAKG1_HUMAN (5-322): 4.33e-107: 317: 33.33
+	Hs
		870991 AAPK2_HUMAN (9-528): 2.35e-154: 454: 28.93		AAKG1_HUMAN (5-322): 4.33e-107: 317: 33.33
+	Sp
		251676 SNF1_SCHPO (1-531): 3.64e-152: 449: 29.56		AAKG_SCHPO (1-334): 1.18e-106: 316: 100.00
+	At
		1105350 KIN10_ARATH (8-531): 6.2e-169: 489: 27.32		SNF4_ARATH (8-314): 5.75e-86: 268: 23.46
+	At
		955218 KIN11_ARATH (22-531): 5.69e-166: 482: 26.40		SNF4_ARATH (8-314): 5.75e-86: 268: 23.46
+	Zm
		1164295 Q6RXY1_MAIZE (9-531): 2.68e-163: 475: 28.34		Q9FUY5_MAIZE (4-314): 2.41e-85: 267: 22.38
+	Sc
		419783 SNF1_YEAST (3-532): 2.65e-153: 454: 28.50		AAKG_YEAST (3-315): 9.96e-91: 275: 50.16
+	Sc
		419869 SNF1_YEAST (3-532): 2.65e-153: 454: 28.50		IMDH2_YEAST (7-333): 6.07e-69: 225: 12.84
+	At
		187510 CIPKB_ARATH (4-345): 7.83e-139: 410: 27.60		SNF4_ARATH (8-314): 5.75e-86: 268: 23.46
+	Sc
		419922 SNF1_YEAST (3-532): 2.65e-153: 454: 28.50		IMDH4_YEAST (7-333): 4.16e-66: 218: 12.50
+	Sc
		419923 SNF1_YEAST (3-532): 2.65e-153: 454: 28.50		IMDH3_YEAST (7-333): 4.34e-64: 213: 12.81
+	At
		955208 KIN11_ARATH (22-531): 5.69e-166: 482: 26.40		KING1_ARATH (89-319): 4.46e-44: 158: 14.80
+	Hs
		518725 BRSK1_HUMAN (19-276): 3.52e-63: 222: 40.93		IMDH2_HUMAN (17-333): 2.52e-62: 208: 13.84