HitPredict

Interactor 1: PRP19 (O14011)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Complexed with cdc5 protein 8) (RING-type E3 ubiquitin transferase PRP19)
Gene: PRP19

Interactor 2: RU2B (Q7LL14)
Probable U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: msl1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21386897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 488 Sp			1 111
+	Hs
		446840 PRP19_HUMAN (1-487): 1.28e-115: 351: 25.69		SNRPA_HUMAN (3-107): 8.62e-29: 106: 37.96
+	Sp
		144080 PRP19_SCHPO (1-488): 4.18e-104: 321: 96.95		SF3B6_SCHPO (4-101): 5.32e-24: 90: 24.27
+	Hs
		1054665 PRP19_HUMAN (1-487): 1.28e-115: 351: 25.69		RBM39_HUMAN (2-110): 5.64e-11: 59.3: 19.64
+	Sc
		692307 PRP19_YEAST (1-451): 3.74e-64: 217: 19.75		MSL1_YEAST (2-88): 1e-24: 91.6: 37.93
+	Hs
		441345 SNR40_HUMAN (148-398): 1.71e-49: 175: 9.24		RU2B_HUMAN (3-95): 5.36e-30: 108: 50.54
+	Hs
		446738 SNR40_HUMAN (148-398): 1.71e-49: 175: 9.24		SNRPA_HUMAN (3-107): 8.62e-29: 106: 37.96
+	Hs
		1288405 SNR40_HUMAN (148-398): 1.71e-49: 175: 9.24		SF3B6_HUMAN (6-105): 3.53e-29: 103: 27.00
+	Hs
		903629 WDR5_HUMAN (130-360): 3.43e-35: 135: 8.47		SF3B6_HUMAN (6-105): 3.53e-29: 103: 27.00
+	Hs
		1054500 SNR40_HUMAN (148-398): 1.71e-49: 175: 9.24		RBM39_HUMAN (2-110): 5.64e-11: 59.3: 19.64
+	Hs
		745256 SNR40_HUMAN (148-398): 1.71e-49: 175: 9.24		RBMX_HUMAN (6-85): 8.32e-10: 56.1: 31.33
+	Hs
		516438 WDR5_HUMAN (130-360): 3.43e-35: 135: 8.47		PABP1_HUMAN (5-108): 4.2e-19: 82.8: 21.50
+	Hs
		903196 WDR5_HUMAN (130-360): 3.43e-35: 135: 8.47		PABP4_HUMAN (5-90): 4.37e-19: 82.8: 23.60
+	Hs
		196944 PRP4_HUMAN (146-323): 2.21e-25: 110: 6.08		SNRPA_HUMAN (3-107): 8.62e-29: 106: 37.96
+	Hs
		745111 WDR5_HUMAN (130-360): 3.43e-35: 135: 8.47		RBMX_HUMAN (6-85): 8.32e-10: 56.1: 31.33
+	Hs
		209381 PLRG1_HUMAN (128-306): 1.31e-09: 62.3: 7.80		RU2B_HUMAN (3-95): 5.36e-30: 108: 50.54
+	Hs
		197019 PRP4_HUMAN (146-323): 2.21e-25: 110: 6.08		RBM39_HUMAN (2-110): 5.64e-11: 59.3: 19.64
+	Hs
		209383 PLRG1_HUMAN (128-306): 1.31e-09: 62.3: 7.80		SNRPA_HUMAN (3-107): 8.62e-29: 106: 37.96
+	Hs
		920967 GBB1_HUMAN (77-361): 4e-24: 105: 11.83		RBM39_HUMAN (2-110): 5.64e-11: 59.3: 19.64
+	Hs
		209434 PLRG1_HUMAN (128-306): 1.31e-09: 62.3: 7.80		RBM39_HUMAN (2-110): 5.64e-11: 59.3: 19.64