HitPredict

Interactor 1: TOP6A (Q9LZ03)
DNA topoisomerase 6 subunit A (AtTOP6A) (EC 5.6.2.2) (Meiotic recombination protein SPO11-3) (AtSPO11-3) (Protein BRASSINOSTEROID INSENSITIVE 5) (Protein ROOT HAIRLESS 2)
Gene: TOP6A

Interactor 2: TOP6A (Q9LZ03)
DNA topoisomerase 6 subunit A (AtTOP6A) (EC 5.6.2.2) (Meiotic recombination protein SPO11-3) (AtSPO11-3) (Protein BRASSINOSTEROID INSENSITIVE 5) (Protein ROOT HAIRLESS 2)
Gene: TOP6A

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 21798944, 26917763, 16339310
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TOP6A-Spo11_Toprim~TP6A_N
Common GO terms GO:0000287 - magnesium ion binding
GO:0003677 - DNA binding
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 4 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 427
At

1 427
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025