HitPredict

Interactor 1: STRN4 (Q9NRL3)
Striatin-4 (Zinedin)
Gene: STRN4

Interactor 2: PHOCN (Q9Y3A3)
MOB-like protein phocein (2C4D) (Class II mMOB1) (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3)
Gene: MOB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	18782753, 37536630, 19156129
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Mob1_phocein~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0030674 - protein-macromolecule adaptor activity GO:0035331 - negative regulation of hippo signaling GO:0090443 - FAR/SIN/STRIPAK complex GO:0098978 - glutamatergic synapse
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 753 Hs			1 225
+	Hs
		1202595 Q59GV6_HUMAN (15-753): 0: 537: 99.06		PHOCN_HUMAN (1-225): 6.3e-111: 318: 100.00
+	Hs
		1092951 STRN3_HUMAN (2-753): 1.46e-147: 452: 49.63		PHOCN_HUMAN (1-225): 6.3e-111: 318: 100.00
+	Hs
		228656 STRN_HUMAN (36-753): 7e-137: 424: 47.92		PHOCN_HUMAN (1-225): 6.3e-111: 318: 100.00
+	Dm
		92283 D3DML3_DROME (56-753): 4.23e-126: 395: 43.04		MOB4_DROME (1-225): 8.77e-106: 305: 80.00
+	Dm
		1264088 Q9VLT9_DROME (56-753): 6.63e-125: 391: 42.78		MOB4_DROME (1-225): 8.77e-106: 305: 80.00