HitPredict

Interactor 1: MTR4 (O14232)
ATP-dependent RNA helicase mtr4 (EC 3.6.4.-)
Gene: MTR4

Interactor 2: DIS3 (P37202)
Exosome complex exonuclease dis3 (EC 3.1.13.-) (EC 3.1.26.-) (Chromosome disjunction protein 3) (Mitotic control protein dis3) (Ribosomal RNA-processing protein 44)
Gene: DIS3

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30321377, 31064814
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0006401 - RNA catabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1117 Sp			1 970
+	Sp
		143103 YE02_SCHPO (87-1117): 0: 710: 48.18		DIS3_SCHPO (1-970): 0: 1195: 100.00
+	Hs
		787037 MTREX_HUMAN (102-1117): 0: 808: 55.74		RRP44_HUMAN (18-969): 0: 1074: 45.68
+	Sc
		810932 MTR4_YEAST (121-1117): 0: 749: 64.81		RRP44_YEAST (19-968): 0: 1030: 51.68
+	Hs
		786991 MTREX_HUMAN (102-1117): 0: 808: 55.74		DI3L1_HUMAN (18-969): 0: 943: 32.20
+	Sc
		716210 SKI2_YEAST (19-1117): 0: 582: 31.25		RRP44_YEAST (19-968): 0: 1030: 51.68
+	Sp
		624017 DBP2_SCHPO (122-632): 2.57e-88: 297: 11.89		DIS3_SCHPO (1-970): 0: 1195: 100.00
+	Sp
		740416 BRR2_SCHPO (118-693): 1.22e-45: 182: 16.37		DIS3_SCHPO (1-970): 0: 1195: 100.00
+	Sc
		621980 DBP1_YEAST (144-632): 2.74e-82: 282: 11.88		SSD1_YEAST (219-349): 3.45e-20: 99.1: 15.91