HitPredict

Interactor 1: TEA3 (O14248)
Tip elongation aberrant protein 3 (Cell polarity protein tea3)
Gene: TEA3

Interactor 2: TEA1 (P87061)
Tip elongation aberrant protein 1 (Altered polarity protein 8) (Cell polarity protein tea1)
Gene: TEA1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	16222337, 15809031, 21652630
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Kelch_1~Kelch_4, Kelch_4~Kelch_4, Kelch_4~Kelch_5, Kelch_1~Kelch_6
Common GO terms	GO:0000935 - division septum GO:0008360 - regulation of cell shape GO:0032153 - cell division site GO:0051285 - cell cortex of cell tip GO:0061245 - establishment or maintenance of bipolar cell polarity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1125 Sp			1 1147
+	Sp
		145160 TEA3_SCHPO (1-1125): 7.36e-139: 450: 100.00		TEA3_SCHPO (856-1147): 5.07e-12: 72.5: 12.88
+	Hs
		1377320 KLH20_HUMAN (5-346): 1.72e-87: 297: 15.72		KLH20_HUMAN (181-477): 2.79e-49: 187: 15.44
+	Hs
		1120830 KLH20_HUMAN (5-346): 1.72e-87: 297: 15.72		KLH12_HUMAN (232-488): 1.09e-26: 118: 13.41
+	Dr
		1092565 KEP1A_DANRE (4-363): 4.51e-75: 262: 13.16		KEP1A_DANRE (255-496): 1.74e-28: 124: 15.92
+	Hs
		307172 KLHL2_HUMAN (8-351): 6.12e-74: 258: 14.21		KEAP1_HUMAN (251-484): 4.97e-27: 119: 14.77
+	Hs
		307182 KLHL2_HUMAN (8-351): 6.12e-74: 258: 14.21		KLH12_HUMAN (232-488): 1.09e-26: 118: 13.41
+	Dm
		1181839 Q7KSF5_DROME (7-488): 8.74e-69: 248: 12.87		Q7KSF5_DROME (6-196): 4.35e-29: 127: 7.73
+	Hs
		307188 KLHL2_HUMAN (8-351): 6.12e-74: 258: 14.21		KLH17_HUMAN (233-499): 1.22e-25: 115: 13.86
+	Hs
		307225 KLHL2_HUMAN (8-351): 6.12e-74: 258: 14.21		KLH13_HUMAN (253-445): 1.73e-20: 99.5: 15.58
+	Hs
		1377424 KLDC2_HUMAN (88-373): 7.52e-68: 236: 18.64		KLDC2_HUMAN (288-464): 1.7e-17: 88.3: 17.28
+	Hs
		1235436 LZTR1_HUMAN (5-610): 5.99e-46: 180: 11.36		LZTR1_HUMAN (2-273): 7.31e-32: 136: 13.50
+	Hs
		848326 HCFC2_HUMAN (94-410): 6.73e-60: 222: 18.68		HCFC1_HUMAN (2-134): 1.74e-10: 67.9: 11.68
+	Hs
		1153780 KLH10_HUMAN (2-228): 1.87e-31: 133: 14.66		KLH10_HUMAN (6-253): 2.58e-36: 148: 12.50
+	Hs
		1120822 KLH13_HUMAN (14-256): 7.71e-31: 132: 12.27		KLH12_HUMAN (232-488): 1.09e-26: 118: 13.41
+	Hs
		1120821 KLHL9_HUMAN (9-233): 6.1e-30: 128: 13.22		KLH12_HUMAN (232-488): 1.09e-26: 118: 13.41
+	Dm
		1374538 KLHDB_DROME (11-221): 1.37e-41: 164: 18.01		KLHDB_DROME (4-142): 6.05e-13: 75.2: 12.95
+	Dm
		1366016 Q9VGE5_DROME (179-457): 5.13e-29: 125: 12.55		Q9VGE5_DROME (19-181): 1.78e-24: 111: 9.20
+	Hs
		1350479 KLH13_HUMAN (14-256): 7.71e-31: 132: 12.27		KLH13_HUMAN (253-445): 1.73e-20: 99.5: 15.58
+	Hs
		1350368 KLH13_HUMAN (14-256): 7.71e-31: 132: 12.27		KLHL9_HUMAN (304-492): 1.47e-11: 70.6: 11.34