Interactor 1: WIS4 (O14299)
MAP kinase kinase kinase wis4 (EC 2.7.11.25) (MAP kinase kinase kinase wak1) (MAP kinase kinase kinase wik1)
Gene: WIS4

Interactor 2: WIN1 (O74304)
MAP kinase kinase kinase win1 (EC 2.7.11.25)
Gene: WIN1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.800

The method score is based on:

Property Details
Experiments 23389634, 24255738
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004709 - MAP kinase kinase kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0016310 - phosphorylation
GO:0038066 - p38MAPK cascade
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1401
Sp

1 1436
+ Sp
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024