HitPredict

Interactor 1: WIS4 (O14299)
MAP kinase kinase kinase wis4 (EC 2.7.11.25) (MAP kinase kinase kinase wak1) (MAP kinase kinase kinase wik1)
Gene: WIS4

Interactor 2: WIS1 (P33886)
Protein kinase wis1 (EC 2.7.12.2) (Protein kinase sty2)
Gene: WIS1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 9718372, 9321395, 23389634
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016310 - phosphorylation
GO:0038066 - p38MAPK cascade
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1401
Sp

1 605
+ Sp
+ Sc
+ Sc
+ Hs
+ Hs
+ Sp
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Sp
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024