HitPredict

Interactor 1: PUB3 (O14326)
E3 ubiquitin-protein ligase pub3 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase pub3)
Gene: PUB3

Interactor 2: RS27A (P0C016)
Ubiquitin-ribosomal protein eS31A fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31A (40S ribosomal protein S27a)]
Gene: ubi3

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	26771498
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HECT~ubiquitin
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 786 Sp			1 150
+	Sp
		145417 PUB3_SCHPO (1-786): 0: 835: 100.00		RS27B_SCHPO (1-149): 6.18e-53: 166: 100.00
+	Sp
		145418 PUB3_SCHPO (1-786): 0: 835: 100.00		RL402_SCHPO (1-76): 1.48e-41: 136: 100.00
+	Hs
		125347 WWP2_HUMAN (29-786): 0: 736: 36.77		RS27A_HUMAN (1-149): 4.06e-62: 189: 81.46
+	Sc
		408371 RSP5_YEAST (5-786): 0: 755: 55.70		RS31_YEAST (1-149): 1.69e-51: 162: 86.09
+	Hs
		924156 WWP1_HUMAN (31-786): 0: 713: 35.36		RS27A_HUMAN (1-149): 4.06e-62: 189: 81.46
+	Sc
		477293 RSP5_YEAST (5-786): 0: 755: 55.70		UBI4P_YEAST (1-76): 9.21e-41: 141: 100.00
+	Hs
		476414 SMUF1_HUMAN (5-786): 0: 741: 36.02		UBC_HUMAN (1-76): 1.37e-30: 117: 96.05
+	Hs
		125112 WWP2_HUMAN (29-786): 0: 736: 36.77		UBB_HUMAN (1-76): 6.89e-33: 117: 96.05
+	Hs
		125113 WWP2_HUMAN (29-786): 0: 736: 36.77		UBC_HUMAN (1-76): 1.37e-30: 117: 96.05
+	Hs
		924414 SMUF2_HUMAN (3-786): 0: 730: 34.25		RL40_HUMAN (1-87): 1.2e-35: 121: 83.91
+	Hs
		475196 SMUF2_HUMAN (3-786): 0: 730: 34.25		UBB_HUMAN (1-76): 6.89e-33: 117: 96.05
+	Hs
		476403 SMUF2_HUMAN (3-786): 0: 730: 34.25		UBC_HUMAN (1-76): 1.37e-30: 117: 96.05
+	Hs
		475140 ITCH_HUMAN (136-786): 0: 722: 41.27		UBB_HUMAN (1-76): 6.89e-33: 117: 96.05
+	Hs
		476205 ITCH_HUMAN (136-786): 0: 722: 41.27		UBC_HUMAN (1-76): 1.37e-30: 117: 96.05
+	Hs
		476350 WWP1_HUMAN (31-786): 0: 713: 35.36		UBC_HUMAN (1-76): 1.37e-30: 117: 96.05
+	Mm
		924239 HUWE1_MOUSE (178-785): 1.31e-167: 539: 31.28		RS27A_MOUSE (1-149): 4.01e-62: 189: 80.80
+	Mm
		476858 HUWE1_MOUSE (178-785): 1.31e-167: 539: 31.28		UBC_MOUSE (1-121): 3.25e-33: 124: 63.64
+	Hs
		924336 HUWE1_HUMAN (86-785): 1.12e-168: 542: 28.39		RL40_HUMAN (1-87): 1.2e-35: 121: 83.91
+	Hs
		475080 HUWE1_HUMAN (86-785): 1.12e-168: 542: 28.39		UBB_HUMAN (1-76): 6.89e-33: 117: 96.05
+	Hs
		475984 HUWE1_HUMAN (86-785): 1.12e-168: 542: 28.39		UBC_HUMAN (1-76): 1.37e-30: 117: 96.05