HitPredict

Interactor 1: PUB3 (O14326)
E3 ubiquitin-protein ligase pub3 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase pub3)
Gene: PUB3

Interactor 2: RL402 (P0CH07)
Ubiquitin-ribosomal protein eL40B fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40B (60S ribosomal protein L40) (CEP52)]
Gene: uep1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	26771498
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HECT~ubiquitin
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 786 Sp			1 128
+	Sp
		145416 PUB3_SCHPO (1-786): 0: 835: 100.00		RS27A_SCHPO (1-71): 6.05e-32: 112: 100.00
+	Sp
		145417 PUB3_SCHPO (1-786): 0: 835: 100.00		RS27B_SCHPO (1-71): 4.09e-32: 112: 100.00
+	Hs
		924414 SMUF2_HUMAN (3-786): 0: 730: 34.25		RL40_HUMAN (1-128): 3.98e-55: 170: 90.63
+	Sc
		477293 RSP5_YEAST (5-786): 0: 755: 55.70		UBI4P_YEAST (1-76): 1.63e-41: 142: 100.00
+	Sc
		408371 RSP5_YEAST (5-786): 0: 755: 55.70		RS31_YEAST (1-70): 8.49e-32: 111: 100.00
+	Hs
		125347 WWP2_HUMAN (29-786): 0: 736: 36.77		RS27A_HUMAN (1-88): 1.83e-37: 126: 84.09
+	Hs
		125112 WWP2_HUMAN (29-786): 0: 736: 36.77		UBB_HUMAN (1-76): 2.09e-32: 115: 96.05
+	Hs
		475196 SMUF2_HUMAN (3-786): 0: 730: 34.25		UBB_HUMAN (1-76): 2.09e-32: 115: 96.05
+	Hs
		924156 WWP1_HUMAN (31-786): 0: 713: 35.36		RS27A_HUMAN (1-88): 1.83e-37: 126: 84.09
+	Hs
		475140 ITCH_HUMAN (136-786): 0: 722: 41.27		UBB_HUMAN (1-76): 2.09e-32: 115: 96.05
+	Hs
		924336 HUWE1_HUMAN (86-785): 1.12e-168: 542: 28.39		RL40_HUMAN (1-128): 3.98e-55: 170: 90.63
+	Dm
		89880 D5SHR3_DROME (373-786): 9.67e-173: 505: 45.61		RL40_DROME (1-128): 2.38e-55: 170: 92.19
+	Mm
		924239 HUWE1_MOUSE (178-785): 1.31e-167: 539: 31.28		RS27A_MOUSE (1-88): 2.05e-37: 125: 84.09
+	Hs
		475080 HUWE1_HUMAN (86-785): 1.12e-168: 542: 28.39		UBB_HUMAN (1-76): 2.09e-32: 115: 96.05
+	Sc
		477647 TOM1_YEAST (380-785): 1.5e-150: 490: 41.93		RL40A_YEAST (1-128): 8.56e-54: 166: 96.88
+	Sp
		143368 PTR1_SCHPO (407-784): 6.14e-155: 502: 42.19		UBI4P_SCHPO (1-77): 8.87e-42: 143: 98.70
+	At
		1091758 UPL1_ARATH (265-784): 3.8e-162: 523: 35.68		UBQ3_ARATH (1-77): 4.92e-34: 121: 96.10
+	At
		1091762 UPL2_ARATH (268-784): 1.69e-159: 515: 34.20		UBQ3_ARATH (1-77): 4.92e-34: 121: 96.10
+	Sc
		477424 TOM1_YEAST (380-785): 1.5e-150: 490: 41.93		UBI4P_YEAST (1-76): 1.63e-41: 142: 100.00
+	Sc
		408448 TOM1_YEAST (380-785): 1.5e-150: 490: 41.93		RS31_YEAST (1-70): 8.49e-32: 111: 100.00