HitPredict

Interactor 1: PAB2 (O14327)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Poly(A)-binding protein II) (PABII)
Gene: PAB2

Interactor 2: YBJC (O74823)
Zinc finger CCCH domain-containing protein C337.12
Gene: SPBC337.12

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.874

Property	Details
Experiments	24713849, 25989903, 26771498, 23658229
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0016604 - nuclear body GO:0033621 - nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 166 Sp			1 376
+	Sp
		252058 NCBP2_SCHPO (54-164): 2.97e-31: 112: 28.57		YBJC_SCHPO (1-376): 0: 556: 100.00
+	Sp
		142718 NOP12_SCHPO (54-161): 1.8e-18: 82.9: 32.11		YBJC_SCHPO (1-376): 0: 556: 100.00
+	Dm
		1181385 PABP2_DROME (3-166): 1.78e-34: 121: 42.19		ZC3H3_DROME (151-374): 1.77e-45: 166: 23.66
+	Hs
		1031384 PABP4_HUMAN (3-139): 5.85e-24: 98.8: 18.12		ZC3H3_HUMAN (175-365): 6.76e-49: 178: 30.26
+	Hs
		1221460 PABP3_HUMAN (3-144): 2.55e-21: 91.5: 16.78		ZC3H3_HUMAN (175-365): 6.76e-49: 178: 30.26
+	Dm
		1364313 Q9VE52_DROME (43-154): 1.12e-30: 116: 27.43		CPSF4_DROME (201-332): 8.83e-43: 152: 31.88
+	Hs
		317856 CSTFT_HUMAN (44-128): 2.76e-21: 91.3: 33.72		CPSF4_HUMAN (201-332): 5.05e-45: 157: 30.66
+	Hs
		317813 CSTF2_HUMAN (46-128): 5.78e-20: 87.5: 32.14		CPSF4_HUMAN (201-332): 5.05e-45: 157: 30.66
+	Hs
		789482 RBM34_HUMAN (40-140): 2.05e-12: 65.7: 18.49		ZC3H3_HUMAN (175-365): 6.76e-49: 178: 30.26
+	Hs
		853946 NCBP2_HUMAN (18-163): 7.02e-33: 116: 20.41		ZC3H8_HUMAN (182-315): 1.56e-25: 106: 22.14
+	Hs
		1295952 RBM38_HUMAN (24-166): 7.87e-31: 113: 15.39		ZC3HA_HUMAN (233-319): 4.6e-16: 81.1: 20.77
+	Sp
		145436 PAB2_SCHPO (1-166): 2.28e-39: 132: 100.00		YQC1_SCHPO (262-371): 3.45e-09: 60.3: 23.28
+	Hs
		1199044 PABP2_HUMAN (2-166): 4.13e-33: 120: 44.94		MKRN2_HUMAN (229-284): 1.24e-10: 64.4: 29.31
+	Hs
		62097 EPAB2_HUMAN (6-165): 2.36e-33: 120: 39.39		MKRN2_HUMAN (229-284): 1.24e-10: 64.4: 29.31
+	Hs
		516728 PABP1_HUMAN (3-144): 5.34e-24: 99.2: 16.78		MKRN1_HUMAN (205-255): 1.27e-10: 64.5: 29.63
+	Hs
		516684 PABP1_HUMAN (3-144): 5.34e-24: 99.2: 16.78		MKRN2_HUMAN (229-284): 1.24e-10: 64.4: 29.31
+	Hs
		1031488 PABP4_HUMAN (3-139): 5.85e-24: 98.8: 18.12		MKRN1_HUMAN (205-255): 1.27e-10: 64.5: 29.63
+	Hs
		1031454 PABP4_HUMAN (3-139): 5.85e-24: 98.8: 18.12		MKRN2_HUMAN (229-284): 1.24e-10: 64.4: 29.31
+	Hs
		963580 TIAR_HUMAN (49-144): 3.2e-20: 87.3: 16.50		MKRN1_HUMAN (205-255): 1.27e-10: 64.5: 29.63
+	Hs
		789510 RBM34_HUMAN (40-140): 2.05e-12: 65.7: 18.49		ZC3HA_HUMAN (233-319): 4.6e-16: 81.1: 20.77