HitPredict

Interactor 1: PAB2 (O14327)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Poly(A)-binding protein II) (PABII)
Gene: PAB2

Interactor 2: PABP (P31209)
Polyadenylate-binding protein, cytoplasmic and nuclear (PABP) (Poly(A)-binding protein) (Polyadenylate tail-binding protein)
Gene: pab1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19336419
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008143 - poly(A) binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 166 Sp			1 653
+	Sc
		376818 SGN1_YEAST (1-165): 2.77e-33: 119: 31.93		PABP_YEAST (2-264): 1.46e-23: 107: 16.35
+	Hs
		516355 PABP1_HUMAN (3-144): 5.34e-24: 99.2: 16.78		NUCL_HUMAN (18-246): 1.97e-29: 126: 22.85
+	Sc
		376958 NCBP2_YEAST (32-166): 2.48e-32: 116: 26.95		PABP_YEAST (2-264): 1.46e-23: 107: 16.35
+	Hs
		853881 NCBP2_HUMAN (18-163): 7.02e-33: 116: 20.41		PABP4_HUMAN (12-173): 4.65e-22: 103: 17.16
+	Hs
		1199032 PABP2_HUMAN (2-166): 4.13e-33: 120: 44.94		PABP5_HUMAN (2-161): 6.96e-20: 94.2: 17.50
+	Hs
		516495 PABP1_HUMAN (3-144): 5.34e-24: 99.2: 16.78		PABP4_HUMAN (12-173): 4.65e-22: 103: 17.16
+	Hs
		516576 PABP2_HUMAN (2-166): 4.13e-33: 120: 44.94		PABP1_HUMAN (354-452): 5.7e-13: 74.2: 25.00
+	Hs
		516635 PABP1_HUMAN (3-144): 5.34e-24: 99.2: 16.78		PABP5_HUMAN (2-161): 6.96e-20: 94.2: 17.50
+	Hs
		1119141 PAP1L_HUMAN (3-144): 2.89e-23: 96.9: 14.69		PABP5_HUMAN (2-161): 6.96e-20: 94.2: 17.50
+	Hs
		516425 NCBP2_HUMAN (18-163): 7.02e-33: 116: 20.41		PABP1_HUMAN (354-452): 5.7e-13: 74.2: 25.00
+	Zm
		8143 A0A1D6ELH4_MAIZE (14-142): 9.87e-22: 92.7: 15.27		A0A1D6ELH4_MAIZE (10-267): 4.43e-20: 96.5: 14.02
+	Hs
		474021 PABP4_HUMAN (3-139): 5.85e-24: 98.8: 18.12		PAB4L_HUMAN (355-449): 9.23e-14: 75.3: 26.04
+	Hs
		516339 PABP1_HUMAN (3-144): 5.34e-24: 99.2: 16.78		PABP1_HUMAN (354-452): 5.7e-13: 74.2: 25.00
+	Hs
		516689 PABP1_HUMAN (3-144): 5.34e-24: 99.2: 16.78		PABP3_HUMAN (354-452): 1.21e-11: 69.9: 24.00
+	Hs
		516471 TIAR_HUMAN (49-144): 3.2e-20: 87.3: 16.50		PABP1_HUMAN (354-452): 5.7e-13: 74.2: 25.00
+	Mm
		665745 TIA1_MOUSE (50-143): 3.76e-20: 87.3: 18.95		PABP1_MOUSE (354-452): 6.55e-13: 73.8: 25.00