HitPredict

Interactor 1: YB45 (O14351)
Uncharacterized oxidoreductase C30D10.05c (EC 1.-.-.-)
Gene: SPBC30D10.05c

Interactor 2: YB45 (O14351)
Uncharacterized oxidoreductase C30D10.05c (EC 1.-.-.-)
Gene: SPBC30D10.05c

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.806

Property	Details
Experiments	26771498, 23695164
Identification Methods	two hybrid, protein complementation assay, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	adh_short~adh_short
Common GO terms	GO:0004757 - sepiapterin reductase (NADP+) activity GO:0005634 - nucleus GO:0005829 - cytosol GO:0006729 - tetrahydrobiopterin biosynthetic process GO:0050664 - oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 247 Sp			1 247
+	Hs
		1312485 DHRS4_HUMAN (1-245): 2.44e-80: 244: 28.13		DHRS4_HUMAN (1-245): 2.44e-80: 244: 28.13
+	Dm
		1248591 Q8SX57_DROME (1-245): 9.01e-79: 239: 26.48		Q8SX57_DROME (1-245): 9.01e-79: 239: 26.48
+	Dm
		1248593 Q8SX57_DROME (1-245): 9.01e-79: 239: 26.48		Q9VNF3_DROME (1-245): 3.33e-78: 238: 25.69
+	Dm
		1214104 Q8SX57_DROME (1-245): 9.01e-79: 239: 26.48		Q8IPP8_DROME (1-245): 9.87e-77: 234: 25.69
+	Dm
		1214105 Q9VNF3_DROME (1-245): 3.33e-78: 238: 25.69		Q8IPP8_DROME (1-245): 9.87e-77: 234: 25.69
+	Ce
		1341704 Q9N5G3_CAEEL (1-245): 1.52e-77: 236: 26.92		Q9N5G3_CAEEL (1-245): 1.52e-77: 236: 26.92
+	Ss
		1259264 DHRS4_PIG (4-245): 3.34e-76: 233: 26.80		DHRS4_PIG (4-245): 3.34e-76: 233: 26.80
+	At
		1338081 TRNHF_ARATH (3-245): 1.06e-77: 236: 23.81		TRNHC_ARATH (3-245): 1.06e-72: 224: 22.62
+	At
		1338080 TRNHF_ARATH (3-245): 1.06e-77: 236: 23.81		SAG13_ARATH (3-245): 4.61e-72: 222: 21.83
+	Ce
		220378 Q19774_CAEEL (1-245): 7.04e-75: 230: 27.52		O45709_CAEEL (1-245): 5.63e-74: 228: 28.30
+	Ec
		468348 FABG_ECOLI (3-245): 8.86e-75: 228: 22.18		FABG_ECOLI (3-245): 8.86e-75: 228: 22.18
+	Sc
		775987 YIV5_YEAST (6-243): 4.05e-74: 227: 42.21		YIV5_YEAST (6-243): 4.05e-74: 227: 42.21
+	At
		1338079 TRNHF_ARATH (3-245): 1.06e-77: 236: 23.81		TRNHA_ARATH (3-245): 1.2e-68: 213: 23.02
+	At
		1378415 TRNHC_ARATH (3-245): 1.06e-72: 224: 22.62		SAG13_ARATH (3-245): 4.61e-72: 222: 21.83
+	Hs
		1162732 DHRS4_HUMAN (1-245): 2.44e-80: 244: 28.13		DR4L2_HUMAN (1-177): 2.39e-59: 188: 28.72