HitPredict

Interactor 1: TOR1 (O14356)
Serine/threonine-protein kinase tor1 (EC 2.7.11.1) (Phosphatidylinositol kinase homolog tor1) (Target of rapamycin kinase 1)
Gene: TOR1

Interactor 2: MIP1 (P87141)
Target of rapamycin complex 1 subunit mip1 (TORC1 subunit mip1)
Gene: MIP1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	19417002, 17261596
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PI3_PI4_kinase~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0031929 - TOR signaling GO:0031931 - TORC1 complex GO:0051321 - meiotic cell cycle
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2335 Sp			1 1313
+	Sp
		953404 TOR2_SCHPO (1-2335): 0: 1803: 51.84		MIP1_SCHPO (1-1313): 0: 1433: 100.00
+	Hs
		787522 MTOR_HUMAN (2-2335): 0: 1603: 39.63		RPTOR_HUMAN (59-1303): 0: 1213: 38.27
+	Mm
		59970 MTOR_MOUSE (2-2335): 0: 1596: 39.39		A4FUW1_MOUSE (59-1303): 0: 1211: 38.05
+	Mm
		1225302 MTOR_MOUSE (2-2335): 0: 1596: 39.39		RPTOR_MOUSE (59-1303): 0: 1206: 36.46
+	Sc
		715187 TOR1_YEAST (2-2335): 0: 1721: 43.40		KOG1_YEAST (466-1305): 3.54e-146: 484: 31.65
+	Sc
		696499 TOR2_YEAST (4-2335): 0: 1719: 44.44		KOG1_YEAST (466-1305): 3.54e-146: 484: 31.65
+	Hs
		787538 MTOR_HUMAN (2-2335): 0: 1603: 39.63		FBXW7_HUMAN (1076-1311): 6.28e-56: 210: 13.92
+	Mm
		1257393 MTOR_MOUSE (2-2335): 0: 1596: 39.39		FBXW7_MOUSE (1076-1311): 9.85e-56: 209: 13.92
+	Hs
		787437 MTOR_HUMAN (2-2335): 0: 1603: 39.63		WDR5_HUMAN (1129-1312): 3.49e-52: 188: 13.59
+	At
		1275308 TOR_ARATH (13-2335): 0: 1660: 38.74		RTOR1_ARATH (1160-1312): 1.96e-10: 67.9: 12.20
+	Dm
		1369191 TOR_DROME (2-2335): 0: 1596: 38.57		Q9W437_DROME (1033-1301): 3.48e-21: 102: 22.96
+	Hs
		209502 TRRAP_HUMAN (319-2334): 0: 838: 14.31		PLRG1_HUMAN (816-1313): 1.68e-83: 284: 13.80
+	Ce
		107371 TOR_CAEEL (2-2335): 0: 1036: 24.76		G5EF88_CAEEL (645-1263): 1.89e-13: 77.9: 11.44
+	Hs
		903639 TRRAP_HUMAN (319-2334): 0: 838: 14.31		WDR5_HUMAN (1129-1312): 3.49e-52: 188: 13.59
+	Hs
		944360 PRKDC_HUMAN (4-2334): 0: 762: 14.96		FBXW7_HUMAN (1076-1311): 6.28e-56: 210: 13.92
+	Hs
		903121 PRKDC_HUMAN (4-2334): 0: 762: 14.96		WDR5_HUMAN (1129-1312): 3.49e-52: 188: 13.59
+	Hs
		1268215 GCN1_HUMAN (26-1141): 2.7e-33: 144: 10.92		FBXW7_HUMAN (1076-1311): 6.28e-56: 210: 13.92
+	Hs
		903400 GCN1_HUMAN (26-1141): 2.7e-33: 144: 10.92		WDR5_HUMAN (1129-1312): 3.49e-52: 188: 13.59