HitPredict

Interactor 1: TOR1 (O14356)
Serine/threonine-protein kinase tor1 (EC 2.7.11.1) (Phosphatidylinositol kinase homolog tor1) (Target of rapamycin kinase 1)
Gene: TOR1

Interactor 2: RICTR (Q09743)
Target of rapamycin complex 2 subunit ste20 (TORC2 subunit ste20)
Gene: ste20

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.951

Property	Details
Experiments	28264193, 17046992, 27206859, 25590601, 18076573, 17261596, 22645648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FRB_dom~RICTOR_N
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031932 - TORC2 complex GO:0038203 - TORC2 signaling and 1 others more... GO:0051321 - meiotic cell cycle
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2335 Sp			1 1309
+	Sp
		999867 TOR2_SCHPO (1-2335): 0: 1803: 51.84		RICTR_SCHPO (1-1309): 0: 1886: 100.00
+	Sc
		696504 TOR2_YEAST (4-2335): 0: 1719: 44.44		TSC11_YEAST (233-1188): 0: 973: 27.53
+	Hs
		787507 MTOR_HUMAN (2-2335): 0: 1603: 39.63		RICTR_HUMAN (238-1221): 0: 1062: 27.03
+	Mm
		1163330 MTOR_MOUSE (2-2335): 0: 1596: 39.39		RICTR_MOUSE (238-1220): 0: 1046: 27.44
+	Ce
		107816 TOR_CAEEL (2-2335): 0: 1036: 24.76		G5EFN2_CAEEL (238-1166): 0: 924: 18.92
+	Dm
		1369189 TOR_DROME (2-2335): 0: 1596: 38.57		Q9VWJ6_DROME (247-630): 2.2e-102: 362: 22.08
+	Hs
		787525 MTOR_HUMAN (2-2335): 0: 1603: 39.63		Q8N6M7_HUMAN (238-438): 1.39e-67: 230: 20.87
+	Hs
		944292 PRKDC_HUMAN (4-2334): 0: 762: 14.96		RICTR_HUMAN (238-1221): 0: 1062: 27.03
+	Hs
		1163769 GCN1_HUMAN (26-1141): 2.7e-33: 144: 10.92		RICTR_HUMAN (238-1221): 0: 1062: 27.03