HitPredict

Interactor 1: RPB7 (O14459)
DNA-directed RNA polymerase II subunit rpb7 (RNA polymerase II subunit B7)
Gene: RPB7

Interactor 2: RPB3 (P37382)
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide)
Gene: RPB3

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.724

Property	Details
Experiments	16204182, 10523639, 11839823, 10648788, 9325316, 11168400
Identification Methods	affinity chromatography technology, biochemical, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005665 - RNA polymerase II, core complex GO:0005829 - cytosol GO:0016591 - RNA polymerase II, holoenzyme
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 172 Sp			1 297
+	Sc
		557982 RPB7_YEAST (3-172): 2.83e-65: 199: 52.94		RPB3_YEAST (2-294): 6.63e-121: 350: 49.36
+	Hs
		169827 RPB7_HUMAN (3-172): 7.42e-65: 197: 49.42		RPAC1_HUMAN (2-269): 1.02e-109: 323: 23.38
+	Hs
		583455 RPB7_HUMAN (3-172): 7.42e-65: 197: 49.42		RPB3_HUMAN (3-274): 2.77e-110: 322: 42.55
+	Sc
		557993 RPC8_YEAST (3-149): 4.1e-44: 146: 20.00		RPB3_YEAST (2-294): 6.63e-121: 350: 49.36
+	Hs
		169999 RPC8_HUMAN (3-172): 2.89e-46: 152: 18.72		RPAC1_HUMAN (2-269): 1.02e-109: 323: 23.38
+	Hs
		583639 RPC8_HUMAN (3-172): 2.89e-46: 152: 18.72		RPB3_HUMAN (3-274): 2.77e-110: 322: 42.55
+	Sc
		429676 RPC8_YEAST (3-149): 4.1e-44: 146: 20.00		RPAC1_YEAST (4-261): 2.14e-96: 289: 25.34