HitPredict

Interactor 1: DLGP1 (O14490)
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene: DLGAP1

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 977 Hs			1 304
+	Hs
		145937 DLGP1_HUMAN (1-977): 0: 1369: 100.00		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		145943 DLGP1_HUMAN (1-977): 0: 1369: 100.00		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		145955 DLGP1_HUMAN (1-977): 0: 1369: 100.00		ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86
+	Hs
		145936 DLGP1_HUMAN (1-977): 0: 1369: 100.00		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		145950 DLGP1_HUMAN (1-977): 0: 1369: 100.00		ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87
+	Mm
		1246939 DLGP1_MOUSE (1-977): 0: 1336: 92.65		SH3K1_MOUSE (114-186): 2.23e-10: 63.3: 21.33
+	Hs
		802758 DLGP2_HUMAN (1-977): 0: 1107: 51.91		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		802783 DLGP4_HUMAN (1-977): 0: 1091: 47.27		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		327231 DLGP3_HUMAN (1-977): 0: 1015: 38.48		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		4616 A0A1B0GTN4_HUMAN (1-977): 0: 1107: 51.91		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		581066 DLGP2_HUMAN (1-977): 0: 1107: 51.91		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		924914 DLGP2_HUMAN (1-977): 0: 1107: 51.91		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		924968 DLGP4_HUMAN (1-977): 0: 1091: 47.27		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		557812 DLGP2_HUMAN (1-977): 0: 1107: 51.91		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		209192 DLGP4_HUMAN (1-977): 0: 1091: 47.27		NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00
+	Hs
		557837 DLGP4_HUMAN (1-977): 0: 1091: 47.27		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		327226 DLGP3_HUMAN (1-977): 0: 1015: 38.48		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		327232 DLGP3_HUMAN (1-977): 0: 1015: 38.48		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		327225 DLGP3_HUMAN (1-977): 0: 1015: 38.48		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00