HitPredict

Interactor 1: DLGP1 (O14490)
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene: DLGAP1

Interactor 2: DLG2 (Q15700)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	32296183, 10844022
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0014069 - postsynaptic density
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 977 Hs			1 870
+	Mm
		1265187 DLGP1_MOUSE (1-977): 0: 1336: 92.65		DLG2_MOUSE (1-870): 0: 740: 94.83
+	Rn
		956992 DLGP1_RAT (1-977): 0: 1334: 92.65		DLG2_RAT (1-870): 0: 740: 94.94
+	Hs
		1077291 DLGP2_HUMAN (1-977): 0: 1107: 51.91		DLG2_HUMAN (1-870): 0: 755: 100.00
+	Hs
		145947 DLGP1_HUMAN (1-977): 0: 1369: 100.00		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Hs
		145945 DLGP1_HUMAN (1-977): 0: 1369: 100.00		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Hs
		145952 DLGP1_HUMAN (1-977): 0: 1369: 100.00		DLG3_HUMAN (317-573): 1.1e-12: 74.1: 19.40
+	Mm
		251107 DLGP1_MOUSE (1-977): 0: 1336: 92.65		CSKP_MOUSE (24-307): 6.74e-22: 104: 10.62
+	Mm
		1195008 DLGP1_MOUSE (1-977): 0: 1336: 92.65		DLG1_MOUSE (271-573): 6.98e-17: 87.6: 17.48
+	Mm
		1143504 DLGP1_MOUSE (1-977): 0: 1336: 92.65		DLG4_MOUSE (375-573): 1.94e-16: 86: 22.93
+	Rn
		956989 DLGP1_RAT (1-977): 0: 1334: 92.65		DLG1_RAT (271-503): 5.38e-17: 87.9: 17.19
+	Rn
		677775 DLGP1_RAT (1-977): 0: 1334: 92.65		DLG4_RAT (375-573): 1.69e-16: 86.4: 22.93
+	Mm
		936189 DLGP1_MOUSE (1-977): 0: 1336: 92.65		DLG3_MOUSE (273-573): 2.97e-15: 82.5: 16.56
+	Rn
		956990 DLGP1_RAT (1-977): 0: 1334: 92.65		DLG3_RAT (273-573): 1.44e-15: 83.3: 16.23
+	Hs
		4618 A0A1B0GTN4_HUMAN (1-977): 0: 1107: 51.91		MPP7_HUMAN (7-359): 1.15e-23: 108: 13.61
+	Hs
		159281 DLGP2_HUMAN (1-977): 0: 1107: 51.91		CSKP_HUMAN (24-307): 6.74e-22: 104: 10.62
+	Hs
		4613 A0A1B0GTN4_HUMAN (1-977): 0: 1107: 51.91		CSKP_HUMAN (24-307): 6.74e-22: 104: 10.62
+	Hs
		1021580 DLGP2_HUMAN (1-977): 0: 1107: 51.91		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Hs
		4617 A0A1B0GTN4_HUMAN (1-977): 0: 1107: 51.91		DLG1_HUMAN (266-573): 3.79e-18: 91.8: 17.83
+	Hs
		942392 DLGP2_HUMAN (1-977): 0: 1107: 51.91		DLG4_HUMAN (375-573): 1.91e-16: 86: 22.93
+	Hs
		4619 A0A1B0GTN4_HUMAN (1-977): 0: 1107: 51.91		DLG3_HUMAN (317-573): 1.1e-12: 74.1: 19.40