HitPredict

Interactor 1: DLGP1 (O14490)
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene: DLGAP1

Interactor 2: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.613

Property	Details
Experiments	35914814, 22558309
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0060090 - molecular adaptor activity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 977 Hs			1 1721
+	Hs
		145955 DLGP1_HUMAN (1-977): 0: 1369: 100.00		ITSN2_HUMAN (1-1720): 0: 723: 54.73
+	Mm
		57877 DLGP1_MOUSE (1-977): 0: 1336: 92.65		KALRN_MOUSE (132-1630): 5.49e-74: 276: 11.30
+	Mm
		1002022 DLGP1_MOUSE (1-977): 0: 1336: 92.65		TRIO_MOUSE (154-1590): 4.99e-70: 264: 11.01
+	Hs
		145936 DLGP1_HUMAN (1-977): 0: 1369: 100.00		NCK1_HUMAN (895-1055): 6.44e-09: 62: 27.75
+	Hs
		557812 DLGP2_HUMAN (1-977): 0: 1107: 51.91		NCK1_HUMAN (895-1055): 6.44e-09: 62: 27.75
+	Hs
		557837 DLGP4_HUMAN (1-977): 0: 1091: 47.27		NCK1_HUMAN (895-1055): 6.44e-09: 62: 27.75
+	Mm
		57846 Q3UVU8_MOUSE (319-911): 0: 812: 92.87		KALRN_MOUSE (132-1630): 5.49e-74: 276: 11.30
+	Hs
		327225 DLGP3_HUMAN (1-977): 0: 1015: 38.48		NCK1_HUMAN (895-1055): 6.44e-09: 62: 27.75
+	Hs
		787918 DLGP5_HUMAN (502-966): 1.34e-126: 406: 18.16		EPS15_HUMAN (529-913): 1.04e-10: 68.9: 12.69