HitPredict

Interactor 1: DLGP1 (O14490)
Disks large-associated protein 1 (DAP-1) (Guanylate kinase-associated protein) (hGKAP) (PSD-95/SAP90-binding protein 1) (SAP90/PSD-95-associated protein 1) (SAPAP1)
Gene: DLGAP1

Interactor 2: DLG3 (Q92796)
Disks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR)
Gene: DLG3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32296183, 9115257
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 977 Hs			1 817
+	Mm
		936189 DLGP1_MOUSE (1-977): 0: 1336: 92.65		DLG3_MOUSE (1-817): 0: 689: 95.05
+	Rn
		956990 DLGP1_RAT (1-977): 0: 1334: 92.65		DLG3_RAT (1-817): 0: 689: 95.17
+	Hs
		145947 DLGP1_HUMAN (1-977): 0: 1369: 100.00		DLG1_HUMAN (13-817): 0: 586: 63.90
+	Mm
		1195008 DLGP1_MOUSE (1-977): 0: 1336: 92.65		DLG1_MOUSE (3-817): 0: 592: 62.63
+	Rn
		956989 DLGP1_RAT (1-977): 0: 1334: 92.65		DLG1_RAT (3-817): 0: 578: 61.42
+	Hs
		4619 A0A1B0GTN4_HUMAN (1-977): 0: 1107: 51.91		DLG3_HUMAN (1-817): 0: 713: 100.00
+	Hs
		1021580 DLGP2_HUMAN (1-977): 0: 1107: 51.91		DLG1_HUMAN (13-817): 0: 586: 63.90
+	Hs
		4617 A0A1B0GTN4_HUMAN (1-977): 0: 1107: 51.91		DLG1_HUMAN (13-817): 0: 586: 63.90
+	Hs
		145945 DLGP1_HUMAN (1-977): 0: 1369: 100.00		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Hs
		145949 DLGP1_HUMAN (1-977): 0: 1369: 100.00		DLG2_HUMAN (312-547): 2.24e-16: 86: 21.40
+	Mm
		1143504 DLGP1_MOUSE (1-977): 0: 1336: 92.65		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25
+	Rn
		677775 DLGP1_RAT (1-977): 0: 1334: 92.65		DLG4_RAT (50-282): 1.36e-25: 115: 20.50
+	Mm
		1265187 DLGP1_MOUSE (1-977): 0: 1336: 92.65		DLG2_MOUSE (312-547): 1.48e-16: 86.4: 21.40
+	Rn
		956992 DLGP1_RAT (1-977): 0: 1334: 92.65		DLG2_RAT (312-547): 1.37e-16: 86.4: 21.40
+	Mm
		251107 DLGP1_MOUSE (1-977): 0: 1336: 92.65		CSKP_MOUSE (106-261): 1.97e-14: 79.8: 16.88
+	Hs
		942392 DLGP2_HUMAN (1-977): 0: 1107: 51.91		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Hs
		1077291 DLGP2_HUMAN (1-977): 0: 1107: 51.91		DLG2_HUMAN (312-547): 2.24e-16: 86: 21.40
+	Hs
		159281 DLGP2_HUMAN (1-977): 0: 1107: 51.91		CSKP_HUMAN (106-261): 1.96e-14: 79.8: 16.88
+	Hs
		4613 A0A1B0GTN4_HUMAN (1-977): 0: 1107: 51.91		CSKP_HUMAN (106-261): 1.96e-14: 79.8: 16.88
+	Hs
		4618 A0A1B0GTN4_HUMAN (1-977): 0: 1107: 51.91		MPP7_HUMAN (101-229): 1.36e-13: 76.4: 16.28