HitPredict

Interactor 1: PLPP3 (O14495)
Phospholipid phosphatase 3 (EC 3.1.3.-) (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b) (Vascular endothelial growth factor and type I collagen-inducible protein) (VCIP)
Gene: PLPP3

Interactor 2: PLPP2 (O43688)
Phospholipid phosphatase 2 (EC 3.1.3.-) (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 2) (PAP2-gamma) (PAP2-G) (Phosphatidate phosphohydrolase type 2c) (Phosphatidic acid phosphatase 2c) (PAP-2c) (PAP2c)
Gene: PLPP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 18215144, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAP2~PAP2
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006644 - phospholipid metabolic process
GO:0006670 - sphingosine metabolic process
GO:0006672 - ceramide metabolic process
and 7 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 311
Hs

1 288
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Last updated: 15 Jul 2024